Giselli Scaini Selected Research

Tyrosine Transaminase (Tyrosine Aminotransferase)

1/2020	Evidence of hippocampal astrogliosis and antioxidant imbalance after L-tyrosine chronic administration in rats.
1/2019	Omega-3 fatty acid supplementation can prevent changes in mitochondrial energy metabolism and oxidative stress caused by chronic administration of L-tyrosine in the brain of rats.
11/2018	Antioxidants Reverse the Changes in the Cholinergic System Caused by L-Tyrosine Administration in Rats.
1/2017	Antioxidants reverse the changes in energy metabolism of rat brain after chronic administration of L.-tyrosine.
1/2017	Omega-3 fatty acid supplementation decreases DNA damage in brain of rats subjected to a chemically induced chronic model of Tyrosinemia type II.
1/2014	L-tyrosine induces DNA damage in brain and blood of rats.

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Giselli Scaini Research Topics

Disease

20	Maple Syrup Urine Disease 01/2022 - 04/2012
13	Tyrosinemias (Tyrosinemia) 01/2020 - 12/2012
11	Mania (Manias) 01/2019 - 02/2008
10	Inflammation (Inflammations) 11/2021 - 01/2017
9	Sepsis (Septicemia) 04/2021 - 09/2008
7	Bipolar Disorder (Manic Depressive Psychosis) 11/2021 - 12/2011
6	Cognitive Dysfunction 11/2020 - 11/2012
6	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 10/2015 - 12/2008
6	Decapitation 08/2015 - 05/2010
5	Body Weight (Weight, Body) 01/2019 - 05/2012
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 01/2017
4	Schizophrenia (Dementia Praecox) 02/2018 - 11/2010
3	Anhedonia 01/2022 - 12/2013
3	Infections 01/2020 - 02/2016
3	Ischemia 02/2018 - 03/2008
3	Acute Kidney Injury (Acute Renal Failure) 06/2014 - 06/2011
3	Brain Diseases (Brain Disorder) 06/2011 - 03/2008
2	Neuroinflammatory Diseases 04/2021 - 11/2020
2	Mood Disorders (Mood Disorder) 01/2021 - 01/2021
2	Meningitis 01/2020 - 08/2009
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2020 - 12/2012
2	Encephalitis (Encephalitis, Rasmussen) 01/2020 - 11/2019
2	Intellectual Disability (Idiocy) 02/2015 - 12/2012
2	Obesity 06/2014 - 06/2012
2	HIV Infections (HIV Infection) 06/2011 - 12/2008
2	Liver Failure 04/2011 - 09/2009
2	Hepatic Encephalopathy 04/2011 - 09/2009
2	Depressive Disorder (Melancholia) 05/2010 - 12/2009
1	Sepsis-Associated Encephalopathy 04/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021

Drug/Important Bio-Agent (IBA)

14	Creatine Kinase (Creatine Phosphokinase)IBA 04/2021 - 02/2008
14	EnzymesIBA 01/2021 - 03/2008
13	Branched-Chain Amino AcidsIBA 01/2022 - 05/2012
13	Tyrosine (L-Tyrosine)FDA Link 01/2020 - 12/2012
12	Oxidoreductases (Dehydrogenase)IBA 01/2022 - 05/2012
12	AntioxidantsIBA 01/2021 - 03/2008
9	AcidsIBA 01/2021 - 02/2012
8	Leucine (L-Leucine)FDA Link 01/2022 - 05/2012
7	Isoleucine (L-Isoleucine)FDA Link 01/2022 - 05/2012
7	Valine (L-Valine)FDA Link 01/2022 - 05/2012
6	Keto AcidsIBA 01/2022 - 05/2012
6	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2017
6	Tyrosine Transaminase (Tyrosine Aminotransferase)IBA 01/2020 - 01/2014
6	Acetylcysteine (Siran)FDA LinkGeneric 02/2018 - 03/2008
6	Citrate (si)-Synthase (Synthase, Citrate)IBA 12/2013 - 05/2010
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2013
5	Brain-Derived Neurotrophic Factor (BDNF)IBA 11/2020 - 09/2013
5	Adenosine Triphosphatases (ATPase)IBA 01/2018 - 02/2010
5	Deferoxamine (Desferal)FDA LinkGeneric 01/2017 - 03/2008
5	Methylphenidate (Ritalin)FDA LinkGeneric 10/2015 - 12/2008
5	BB Form Creatine KinaseIBA 02/2010 - 02/2008
4	CytokinesIBA 01/2020 - 01/2011
4	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2020 - 01/2017
4	Ketamine FDA LinkGeneric 02/2018 - 11/2010
4	Nerve Growth Factor (NGF)IBA 01/2018 - 12/2013
4	Valproic Acid (Depakote)FDA LinkGeneric 01/2017 - 02/2008
4	LithiumIBA 01/2017 - 02/2008
3	Nerve Growth Factors (Neurotrophins)IBA 01/2022 - 10/2014
3	Mitochondrial DNA (mtDNA)IBA 11/2021 - 12/2017
3	Interleukin-6 (Interleukin 6)IBA 11/2019 - 01/2018
3	Antidepressive Agents (Antidepressants)IBA 06/2019 - 12/2009
3	Succinate Dehydrogenase (Fumarate Reductase)IBA 01/2018 - 05/2010
3	DNA (Deoxyribonucleic Acid)IBA 11/2017 - 01/2014
3	Biological ProductsIBA 10/2017 - 06/2014
3	fenproporexIBA 01/2017 - 03/2014
3	Free RadicalsIBA 01/2017 - 03/2008
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2017 - 02/2012
3	AcetylcholinesteraseIBA 08/2015 - 04/2012
3	Messenger RNA (mRNA)IBA 12/2013 - 10/2012
2	KynurenineIBA 11/2021 - 02/2018
2	Caspase 3 (Caspase-3)IBA 01/2020 - 06/2014
2	Amino Acids FDA Link 01/2020 - 01/2019
2	Neurotransmitter Agents (Neurotransmitter)IBA 06/2018 - 10/2014
2	Thiobarbituric Acid Reactive SubstancesIBA 02/2018 - 03/2014
2	Antipsychotic Agents (Antipsychotics)IBA 01/2018 - 06/2012
2	Pharmaceutical PreparationsIBA 01/2018 - 10/2015
2	Dopamine (Intropin)FDA LinkGeneric 10/2014 - 06/2012
2	Methylmalonic AcidIBA 06/2014 - 06/2013
2	Gentamicins (Gentamicin)FDA LinkGeneric 06/2014 - 06/2013
2	Amphetamine (Amfetamine)FDA LinkGeneric 04/2014 - 01/2013
2	Dextroamphetamine (Dexedrine)FDA LinkGeneric 12/2011 - 04/2011
2	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2011 - 04/2011
2	Acetaminophen (Paracetamol)FDA LinkGeneric 04/2011 - 09/2009
2	Ouabain (G Strophanthin)IBA 08/2010 - 02/2010
2	salicylhydroxamic acid (SHAM)IBA 06/2010 - 09/2008
1	Hydroxy AcidsIBA 01/2022
1	tianeptine (Stablon)IBA 01/2022
1	teleocalcinIBA 04/2021
1	Glutamic Acid (Glutamate)FDA Link 01/2021
1	Adenosine Triphosphate (ATP)IBA 01/2021
1	Thioctic Acid (Lipoic Acid)IBA 11/2020
1	Fish OilsIBA 11/2020
1	Cardiolipins (Cardiolipin)IBA 01/2020
1	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 01/2020
1	LigandsIBA 01/2020

Therapy/Procedure

8	Ligation 04/2021 - 09/2008
5	Therapeutics 01/2021 - 03/2014
3	Punctures 04/2021 - 06/2011
3	Subcutaneous Injections 01/2018 - 10/2013
1	Aftercare (After-Treatment) 01/2022